KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2A
All Species:
12.73
Human Site:
T140
Identified Species:
21.54
UniProt:
Q9BY44
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BY44
NP_114414.2
585
64990
T140
P
S
W
S
E
D
E
T
L
C
A
R
N
V
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108004
580
64436
N140
D
E
T
L
C
A
R
N
V
N
N
E
V
H
F
Dog
Lupus familis
XP_534306
585
65159
T140
P
S
W
S
E
D
E
T
I
C
A
R
N
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJW6
581
64385
I140
P
S
W
S
D
D
E
I
I
C
A
R
N
V
N
Rat
Rattus norvegicus
NP_001102809
541
60196
G138
N
D
F
N
L
S
P
G
T
Q
P
F
K
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507598
493
54394
Q90
F
V
L
S
P
G
A
Q
P
S
K
V
A
V
Y
Chicken
Gallus gallus
Q5ZKC1
586
64485
S140
P
C
W
A
D
D
E
S
I
C
A
R
N
V
N
Frog
Xenopus laevis
Q7ZY11
582
64798
D140
W
S
P
H
W
S
D
D
E
N
I
C
A
R
N
Zebra Danio
Brachydanio rerio
Q4QRJ7
580
64206
I140
S
W
A
D
D
E
S
I
S
V
R
N
V
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNX8
638
70052
S152
P
S
W
S
A
D
E
S
I
F
A
L
V
V
G
Honey Bee
Apis mellifera
XP_625143
577
65273
K140
P
Q
W
T
S
D
E
K
V
C
G
M
L
V
G
Nematode Worm
Caenorhab. elegans
Q19052
570
64001
S141
A
S
W
E
P
Q
F
S
D
D
E
S
L
A
A
Sea Urchin
Strong. purpuratus
XP_001186352
299
33040
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53235
642
71286
G145
F
S
K
L
D
N
Y
G
L
R
L
F
K
H
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.4
96
N.A.
92.8
82.5
N.A.
74.5
84.4
74.8
69.5
N.A.
39
43.9
35.7
29.2
Protein Similarity:
100
N.A.
98.2
98.2
N.A.
95.5
87
N.A.
79.4
91.6
86.5
81.5
N.A.
56.5
61.3
54.8
40
P-Site Identity:
100
N.A.
0
93.3
N.A.
80
6.6
N.A.
13.3
66.6
13.3
6.6
N.A.
53.3
40
13.3
0
P-Site Similarity:
100
N.A.
6.6
100
N.A.
93.3
20
N.A.
13.3
93.3
20
20
N.A.
66.6
53.3
20
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
8
8
8
0
0
0
36
0
15
8
15
% A
% Cys:
0
8
0
0
8
0
0
0
0
36
0
8
0
0
0
% C
% Asp:
8
8
0
8
29
43
8
8
8
8
0
0
0
0
8
% D
% Glu:
0
8
0
8
15
8
43
0
8
0
8
8
0
0
0
% E
% Phe:
15
0
8
0
0
0
8
0
0
8
0
15
0
0
8
% F
% Gly:
0
0
0
0
0
8
0
15
0
0
8
0
0
0
15
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
15
29
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
8
0
0
8
0
15
0
0
% K
% Leu:
0
0
8
15
8
0
0
0
15
0
8
8
15
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
8
0
8
0
8
0
15
8
8
29
8
43
% N
% Pro:
43
0
8
0
15
0
8
0
8
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
8
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
8
8
29
0
8
0
% R
% Ser:
8
50
0
36
8
15
8
22
8
8
0
8
0
0
0
% S
% Thr:
0
0
8
8
0
0
0
15
8
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
15
8
0
8
22
58
0
% V
% Trp:
8
8
50
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _